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GATA6 is a regulator of sinus node development and heart rhythm

The sinus node (SAN) is the primary pacemaker of the human heart, and abnormalities in its structure or function cause sick sinus syndrome, the most common reason for electronic pacemaker implantation. Here we report that transcription factor GATA6, whose mutations in humans are linked to arrhythmia...

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Detalles Bibliográficos
Autores principales: Gharibeh, Lara, Yamak, Abir, Whitcomb, Jamieson, Lu, Aizhu, Joyal, Mathieu, Komati, Hiba, Liang, Wenbin, Fiset, Céline, Nemer, Mona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817143/
https://www.ncbi.nlm.nih.gov/pubmed/33443158
http://dx.doi.org/10.1073/pnas.2007322118