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GATA6 is a regulator of sinus node development and heart rhythm
The sinus node (SAN) is the primary pacemaker of the human heart, and abnormalities in its structure or function cause sick sinus syndrome, the most common reason for electronic pacemaker implantation. Here we report that transcription factor GATA6, whose mutations in humans are linked to arrhythmia...
Autores principales: | Gharibeh, Lara, Yamak, Abir, Whitcomb, Jamieson, Lu, Aizhu, Joyal, Mathieu, Komati, Hiba, Liang, Wenbin, Fiset, Céline, Nemer, Mona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817143/ https://www.ncbi.nlm.nih.gov/pubmed/33443158 http://dx.doi.org/10.1073/pnas.2007322118 |
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