Cargando…
Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium
Skin epithelium can accumulate a high burden of oncogenic mutations without morphological or functional consequences. To investigate the mechanism of oncogenic tolerance, we induced Hras(G12V) in single murine epidermal cells and followed them long term. We observed that Hras(G12V) promotes an early...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817173/ https://www.ncbi.nlm.nih.gov/pubmed/33393458 http://dx.doi.org/10.7554/eLife.54618 |