ARL3 activation requires the co-GEF BART and effector-mediated turnover

The ADP-ribosylation factor-like 3 (ARL3) is a ciliopathy G-protein which regulates the ciliary trafficking of several lipid-modified proteins. ARL3 is activated by its guanine exchange factor (GEF) ARL13B via an unresolved mechanism. BART is described as an ARL3 effector which has also been implica...

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Detalles Bibliográficos
Autores principales: ElMaghloob, Yasmin, Sot, Begoña, McIlwraith, Michael J, Garcia, Esther, Yelland, Tamas, Ismail, Shehab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817177/
https://www.ncbi.nlm.nih.gov/pubmed/33438581
http://dx.doi.org/10.7554/eLife.64624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817177/
https://www.ncbi.nlm.nih.gov/pubmed/33438581
http://dx.doi.org/10.7554/eLife.64624

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