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Deep-learning-based three-dimensional label-free tracking and analysis of immunological synapses of CAR-T cells

The immunological synapse (IS) is a cell-cell junction between a T cell and a professional antigen-presenting cell. Since the IS formation is a critical step for the initiation of an antigen-specific immune response, various live-cell imaging techniques, most of which rely on fluorescence microscopy...

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Detalles Bibliográficos
Autores principales: Lee, Moosung, Lee, Young-Ho, Song, Jinyeop, Kim, Geon, Jo, YoungJu, Min, HyunSeok, Kim, Chan Hyuk, Park, YongKeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817186/
https://www.ncbi.nlm.nih.gov/pubmed/33331817
http://dx.doi.org/10.7554/eLife.49023