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Deep-learning-based three-dimensional label-free tracking and analysis of immunological synapses of CAR-T cells
The immunological synapse (IS) is a cell-cell junction between a T cell and a professional antigen-presenting cell. Since the IS formation is a critical step for the initiation of an antigen-specific immune response, various live-cell imaging techniques, most of which rely on fluorescence microscopy...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817186/ https://www.ncbi.nlm.nih.gov/pubmed/33331817 http://dx.doi.org/10.7554/eLife.49023 |