Unexpected Transcriptional Programs Contribute to Hippocampal Memory Deficits and Neuronal Stunting after Early-Life Adversity

Early-life adversity (ELA) is associated with lifelong memory deficits, yet the responsible mechanisms remain unclear. We impose ELA by rearing rat pups in simulated poverty, assess hippocampal memory, and probe changes in gene expression, their transcriptional regulation, and the consequent changes...

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Detalles Bibliográficos
Autores principales: Bolton, Jessica L., Schulmann, Anton, Garcia-Curran, Megan M., Regev, Limor, Chen, Yuncai, Kamei, Noriko, Shao, Manlin, Singh-Taylor, Akanksha, Jiang, Shan, Noam, Yoav, Molet, Jenny, Mortazavi, Ali, Baram, Tallie Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817243/
https://www.ncbi.nlm.nih.gov/pubmed/33326786
http://dx.doi.org/10.1016/j.celrep.2020.108511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817243/
https://www.ncbi.nlm.nih.gov/pubmed/33326786
http://dx.doi.org/10.1016/j.celrep.2020.108511

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