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Analogue discovery of safer alternatives to HCQ and CQ drugs for SAR-CoV-2 by computational design

COVID-19 outbreak poses a severe health emergency to the global community. Due to availability of limited data, the selection of an effective treatment is a challenge. Hydroxychloroquine (HCQ), a chloroquine (CQ) derivative administered for malaria and autoimmune diseases, has been shown to be effec...

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Detalles Bibliográficos
Autores principales: Sinha, Meetali, Gupta, Anshika, Gupta, Shristee, Singh, Prakrity, Pandit, Shraddha, Chauhan, Shweta Singh, Parthasarathi, Ramakrishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817420/
https://www.ncbi.nlm.nih.gov/pubmed/33535144
http://dx.doi.org/10.1016/j.compbiomed.2021.104222