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Analogue discovery of safer alternatives to HCQ and CQ drugs for SAR-CoV-2 by computational design
COVID-19 outbreak poses a severe health emergency to the global community. Due to availability of limited data, the selection of an effective treatment is a challenge. Hydroxychloroquine (HCQ), a chloroquine (CQ) derivative administered for malaria and autoimmune diseases, has been shown to be effec...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817420/ https://www.ncbi.nlm.nih.gov/pubmed/33535144 http://dx.doi.org/10.1016/j.compbiomed.2021.104222 |