Identification and characterisation of putative drug binding sites in human ATP-binding cassette B5 (ABCB5) transporter

The human ATP-binding cassette B5 (ABCB5) transporter, a member of the ABC transporter superfamily, is linked to chemoresistance in tumour cells by drug effluxion. However, little is known about its structure and drug-binding sites. In this study, we generated an atomistic model of the full-length h...

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Detalles Bibliográficos
Autores principales: Tangella, Lokeswari P., Arooj, Mahreen, Deplazes, Evelyne, Gray, Elin S., Mancera, Ricardo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817430/
https://www.ncbi.nlm.nih.gov/pubmed/33510870
http://dx.doi.org/10.1016/j.csbj.2020.12.042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817430/
https://www.ncbi.nlm.nih.gov/pubmed/33510870
http://dx.doi.org/10.1016/j.csbj.2020.12.042

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