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Identification and characterisation of putative drug binding sites in human ATP-binding cassette B5 (ABCB5) transporter
The human ATP-binding cassette B5 (ABCB5) transporter, a member of the ABC transporter superfamily, is linked to chemoresistance in tumour cells by drug effluxion. However, little is known about its structure and drug-binding sites. In this study, we generated an atomistic model of the full-length h...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817430/ https://www.ncbi.nlm.nih.gov/pubmed/33510870 http://dx.doi.org/10.1016/j.csbj.2020.12.042 |