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A stable platform for the production of virus-like particles pseudotyped with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike protein

In this study, we showed that a codon optimized version of the spike (S) protein of SARS-CoV-2 can migrate to the cell membrane. However, efficient production of Moloney murine leukemia (MLV) infectious viral particles was only achieved with stable expression of a shorter S version in C-terminal (ΔS...

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Detalles Bibliográficos
Autores principales: Roy, Sylvie, Ghani, Karim, de Campos-Lima, Pedro O., Caruso, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817443/
https://www.ncbi.nlm.nih.gov/pubmed/33482242
http://dx.doi.org/10.1016/j.virusres.2021.198305