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Broadening the spectrum of NTRK rearranged mesenchymal tumors and usefulness of pan-TRK immunohistochemistry for identification of NTRK fusions

Fusions involving NTRK1, NTRK2, and NTRK3 are oncogenic drivers occurring in a spectrum of mesenchymal neoplasms ranging from benign to highly malignant tumors. To gain further insights into the staining profile with the pan-TRK assay, we analyzed a large number of soft tissue sarcomas and correlate...

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Detalles Bibliográficos
Autores principales: Brčić, Iva, Godschachner, Theresa Maria, Bergovec, Marko, Igrec, Jasminka, Till, Holger, Lackner, Herwig, Scheipl, Susanne, Kashofer, Karl, Brodowicz, Thomas, Leithner, Andreas, Szkandera, Joanna, Liegl-Atzwanger, Bernadette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817523/
https://www.ncbi.nlm.nih.gov/pubmed/32860002
http://dx.doi.org/10.1038/s41379-020-00657-x