CYLD mutation characterizes a subset of HPV-positive head and neck squamous cell carcinomas with distinctive genomics and frequent cylindroma-like histologic features

Mutations in the tumor suppressor CYLD, known to be causative of cylindromas, were recently described in a subset of high-risk (hr) HPV-positive head and neck squamous cell carcinomas (HNSCC). Pathologic and genetic characterization of these CYLD-mutant carcinomas, however, remains limited. Here, we...

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Detalles Bibliográficos
Autores principales: Williams, Erik A., Montesion, Meagan, Alexander, Brian M., Ramkissoon, Shakti H., Elvin, Julia A., Ross, Jeffrey S., Williams, Kevin Jon, Glomski, Krzysztof, Bledsoe, Jacob R., Tse, Julie Y., Mochel, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817524/
https://www.ncbi.nlm.nih.gov/pubmed/32892208
http://dx.doi.org/10.1038/s41379-020-00672-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817524/
https://www.ncbi.nlm.nih.gov/pubmed/32892208
http://dx.doi.org/10.1038/s41379-020-00672-y

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