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Discovery of the EL-0052 as a potential anesthetic drug
As a γ-aminobutyric acid A receptor (GABA(A)R) inhibitor, etomidate fulfills several characteristics of an ideal anesthetic agent, such as rapid onset with rapid clearance and high potency, along with cardiovascular stability. Unfortunately, etomidate has been reported to inhibit CYP11B1 at hypnotic...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817531/ https://www.ncbi.nlm.nih.gov/pubmed/33510871 http://dx.doi.org/10.1016/j.csbj.2021.01.002 |