BRAF (AMP) Frequently Co-occurs With IDH1/2, TP53, and ATRX Mutations in Adult Patients With Gliomas and Is Associated With Poorer Survival Than That of Patients Harboring BRAF (V600E)

Abnormal RAS/RAF signaling plays a critical role in glioma. Although it is known that the V600E mutation of v-raf murine viral oncogene homolog B1 (BRAF (V600E)) and BRAF amplification (BRAF (AMP)) both result in constitutive activation of the RAS/RAF pathway, whether BRAF (V600E) and BRAF (AMP) hav...

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Detalles Bibliográficos
Autores principales: Da, Rong, Wang, Maode, Jiang, Haitao, Wang, Tuo, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817544/
https://www.ncbi.nlm.nih.gov/pubmed/33489866
http://dx.doi.org/10.3389/fonc.2020.531968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817544/
https://www.ncbi.nlm.nih.gov/pubmed/33489866
http://dx.doi.org/10.3389/fonc.2020.531968

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