Conditional knockdown of integrin beta-3 reveals its involvement in osteolytic and soft tissue lesions of breast cancer skeletal metastasis

Integrin β3 (ITGB3) is probably related to skeletal metastasis, which is the most frequent complication in breast cancer progression. We aimed to define its role and suitability as target for anti-metastatic therapy. We generated two MDA-MB-231 cell clones with conditional miRNA-mediated ITGB3 knock...

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Detalles Bibliográficos
Autores principales: Kovacheva, Marineta, Zepp, Michael, Berger, Stefan, Berger, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article – Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817553/
https://www.ncbi.nlm.nih.gov/pubmed/33083904
http://dx.doi.org/10.1007/s00432-020-03428-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817553/
https://www.ncbi.nlm.nih.gov/pubmed/33083904
http://dx.doi.org/10.1007/s00432-020-03428-y

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