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Genetic Modification of Tumor-Infiltrating Lymphocytes via Retroviral Transduction

Adoptive T cell therapy (ACT) holds great promise for cancer treatment. One approach, which has regained wide interest in recent years, employs antitumor T cells isolated from tumor lesions (“tumor-infiltrating lymphocytes” or TIL). It is now appreciated that a considerable proportion of anti-melano...

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Detalles Bibliográficos
Autores principales: Weinstein-Marom, Hadas, Gross, Gideon, Levi, Michal, Brayer, Hadar, Schachter, Jacob, Itzhaki, Orit, Besser, Michal J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817656/
https://www.ncbi.nlm.nih.gov/pubmed/33488585
http://dx.doi.org/10.3389/fimmu.2020.584148