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Direct reprogramming of epithelial cell rests of malassez into mesenchymal-like cells by epigenetic agents

The DNA demethylating agent, 5-Azacytidine (5Aza), and histone deacetylase inhibitor, valproic acid (Vpa), can improve the reprogramming efficiencies of pluripotent cells. This study aimed to examine the roles of 5Aza and Vpa in the dedifferentiation of epithelial cell rests of Malassez (ERM) into s...

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Detalles Bibliográficos
Autores principales: Yoshida, Koki, Uehara, Osamu, Kurashige, Yoshihito, Paudel, Durga, Onishi, Aya, Neopane, Puja, Hiraki, Daichi, Morikawa, Tetsuro, Harada, Fumiya, Takai, Rie, Sato, Jun, Saitoh, Masato, Abiko, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817677/
https://www.ncbi.nlm.nih.gov/pubmed/33473142
http://dx.doi.org/10.1038/s41598-020-79426-4