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Direct reprogramming of epithelial cell rests of malassez into mesenchymal-like cells by epigenetic agents
The DNA demethylating agent, 5-Azacytidine (5Aza), and histone deacetylase inhibitor, valproic acid (Vpa), can improve the reprogramming efficiencies of pluripotent cells. This study aimed to examine the roles of 5Aza and Vpa in the dedifferentiation of epithelial cell rests of Malassez (ERM) into s...
Autores principales: | Yoshida, Koki, Uehara, Osamu, Kurashige, Yoshihito, Paudel, Durga, Onishi, Aya, Neopane, Puja, Hiraki, Daichi, Morikawa, Tetsuro, Harada, Fumiya, Takai, Rie, Sato, Jun, Saitoh, Masato, Abiko, Yoshihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817677/ https://www.ncbi.nlm.nih.gov/pubmed/33473142 http://dx.doi.org/10.1038/s41598-020-79426-4 |
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