Short H2A histone variants are expressed in cancer

Short H2A (sH2A) histone variants are primarily expressed in the testes of placental mammals. Their incorporation into chromatin is associated with nucleosome destabilization and modulation of alternate splicing. Here, we show that sH2As innately possess features similar to recurrent oncohistone mut...

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Detalles Bibliográficos
Autores principales: Chew, Guo-Liang, Bleakley, Marie, Bradley, Robert K., Malik, Harmit S., Henikoff, Steven, Molaro, Antoine, Sarthy, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817690/
https://www.ncbi.nlm.nih.gov/pubmed/33473122
http://dx.doi.org/10.1038/s41467-020-20707-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817690/
https://www.ncbi.nlm.nih.gov/pubmed/33473122
http://dx.doi.org/10.1038/s41467-020-20707-x

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