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Immunologically programming the tumor microenvironment induces the pattern recognition receptor NLRC4-dependent antitumor immunity

BACKGROUND: The efficacy of cancer immunotherapy can be limited by the poor immunogenicity of cancer and the immunosuppressive tumor microenvironment (TME). Immunologically programming the TME and creating an immune-inflamed tumor phenotype is critical for improving the immune-responsiveness of canc...

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Detalles Bibliográficos
Autores principales: Yu, Xiaofei, Liu, Wenjie, Chen, Shixian, Cheng, Xueqian, Paez, Patrick A, Sun, Tuanwei, Yuan, Fang, Wei, Chunyan, Landry, Joseph W, Poklepovic, Andrew S, Bear, Harry D, Subjeck, John R, Repasky, Elizabeth, Guo, Chunqing, Wang, Xiang-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817794/
https://www.ncbi.nlm.nih.gov/pubmed/33468554
http://dx.doi.org/10.1136/jitc-2020-001595