Cargando…
Immunologically programming the tumor microenvironment induces the pattern recognition receptor NLRC4-dependent antitumor immunity
BACKGROUND: The efficacy of cancer immunotherapy can be limited by the poor immunogenicity of cancer and the immunosuppressive tumor microenvironment (TME). Immunologically programming the TME and creating an immune-inflamed tumor phenotype is critical for improving the immune-responsiveness of canc...
Autores principales: | Yu, Xiaofei, Liu, Wenjie, Chen, Shixian, Cheng, Xueqian, Paez, Patrick A, Sun, Tuanwei, Yuan, Fang, Wei, Chunyan, Landry, Joseph W, Poklepovic, Andrew S, Bear, Harry D, Subjeck, John R, Repasky, Elizabeth, Guo, Chunqing, Wang, Xiang-Yang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817794/ https://www.ncbi.nlm.nih.gov/pubmed/33468554 http://dx.doi.org/10.1136/jitc-2020-001595 |
Ejemplares similares
-
Novel phosphatidylserine-binding molecule enhances antitumor T-cell responses by targeting immunosuppressive exosomes in human tumor microenvironments
por: Bhatta, Maulasri, et al.
Publicado: (2021) -
Vector Aided Microenvironment programming (VAMP): reprogramming the TME with MVA virus expressing IL-12 for effective antitumor activity
por: Seclì, Laura, et al.
Publicado: (2023) -
VCN-01 disrupts pancreatic cancer stroma and exerts antitumor effects
por: Bazan-Peregrino, Miriam, et al.
Publicado: (2021) -
Potent STING activation stimulates immunogenic cell death to enhance antitumor immunity in neuroblastoma
por: Wang-Bishop, Lihong, et al.
Publicado: (2020) -
Elucidating mechanisms of antitumor immunity mediated by live oncolytic vaccinia and heat-inactivated vaccinia
por: Wang, Weiyi, et al.
Publicado: (2021)