TRIM16 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Modulating CHIP-Mediated Degradation of RUNX2

Bone regeneration is the ultimate goal of periodontal therapies, in which osteogenic differentiation of human periodontal ligament stem cells plays a critical role. The tripartite motif (TRIM)16, an E3 ubiquitin ligase, is downregulated in periodontal tissues of patients with periodontitis, while th...

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Detalles Bibliográficos
Autores principales: Zhao, Yi, Zhai, Qiaoli, Liu, Hong, Xi, Xun, Chen, Shuai, Liu, Dongxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817816/
https://www.ncbi.nlm.nih.gov/pubmed/33490087
http://dx.doi.org/10.3389/fcell.2020.625105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817816/
https://www.ncbi.nlm.nih.gov/pubmed/33490087
http://dx.doi.org/10.3389/fcell.2020.625105

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