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TRIM16 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Modulating CHIP-Mediated Degradation of RUNX2
Bone regeneration is the ultimate goal of periodontal therapies, in which osteogenic differentiation of human periodontal ligament stem cells plays a critical role. The tripartite motif (TRIM)16, an E3 ubiquitin ligase, is downregulated in periodontal tissues of patients with periodontitis, while th...
Autores principales: | Zhao, Yi, Zhai, Qiaoli, Liu, Hong, Xi, Xun, Chen, Shuai, Liu, Dongxu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817816/ https://www.ncbi.nlm.nih.gov/pubmed/33490087 http://dx.doi.org/10.3389/fcell.2020.625105 |
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