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Study of influence of the glutamatergic concentration of [(18)F]FPEB binding to metabotropic glutamate receptor subtype 5 with N-acetylcysteine challenge in rats and SRM/PET study in human healthy volunteers

Altered glutamate signaling is thought to be involved in a myriad of psychiatric disorders. Positron emission tomography (PET) imaging with [(18)F]FPEB allows assessing dynamic changes in metabotropic glutamate receptor 5 (mGluR5) availability underlying neuropathological conditions. The influence o...

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Detalles Bibliográficos
Autores principales: Dupont, Anne-Claire, Serrière, Sophie, Barantin, Laurent, Vercouillie, Johnny, Tauber, Clovis, Gissot, Valérie, Bodard, Sylvie, Chicheri, Gabrielle, Chalon, Sylvie, Bonnet-Brilhault, Pr Frédérique, Santiago-Ribeiro, Pr Maria-Joao, Arlicot, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817831/
https://www.ncbi.nlm.nih.gov/pubmed/33473111
http://dx.doi.org/10.1038/s41398-020-01152-2