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Overloaded Adeno-Associated Virus as a Novel Gene Therapeutic Tool for Otoferlin-Related Deafness

Hearing impairment is the most common sensory disorder in humans. So far, rehabilitation of profoundly deaf subjects relies on direct stimulation of the auditory nerve through cochlear implants. However, in some forms of genetic hearing impairment, the organ of Corti is structurally intact and thera...

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Detalles Bibliográficos
Autores principales: Rankovic, Vladan, Vogl, Christian, Dörje, Nele M., Bahader, Iman, Duque-Afonso, Carlos J., Thirumalai, Anupriya, Weber, Thomas, Kusch, Kathrin, Strenzke, Nicola, Moser, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817888/
https://www.ncbi.nlm.nih.gov/pubmed/33488357
http://dx.doi.org/10.3389/fnmol.2020.600051