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Proprotein Convertase Subtilisin/Kexin Type 9 Promotes Gastric Cancer Metastasis and Suppresses Apoptosis by Facilitating MAPK Signaling Pathway Through HSP70 Up-Regulation

OBJECTIVE: To examine the effect of proprotein convertase subtilisin/kexin type 9 (PCSK9) on gastric cancer (GC) progression and prognosis, and to explore the underlying mechanism. METHODS: PCSK9 expression levels in human GC tissues were determined by quantitative real-time PCR, western blotting, a...

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Detalles Bibliográficos
Autores principales: Xu, Beili, Li, Shuyu, Fang, Yong, Zou, Yanting, Song, Dongqiang, Zhang, Shuncai, Cai, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817950/
https://www.ncbi.nlm.nih.gov/pubmed/33489919
http://dx.doi.org/10.3389/fonc.2020.609663