Solvent Accessibility of Residues Undergoing Pathogenic Variations in Humans: From Protein Structures to Protein Sequences

Solvent accessibility (SASA) is a key feature of proteins for determining their folding and stability. SASA is computed from protein structures with different algorithms, and from protein sequences with machine-learning based approaches trained on solved structures. Here we ask the question as to wh...

Descripción completa

Detalles Bibliográficos
Autores principales: Savojardo, Castrense, Manfredi, Matteo, Martelli, Pier Luigi, Casadio, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817970/
https://www.ncbi.nlm.nih.gov/pubmed/33490109
http://dx.doi.org/10.3389/fmolb.2020.626363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817970/
https://www.ncbi.nlm.nih.gov/pubmed/33490109
http://dx.doi.org/10.3389/fmolb.2020.626363

Ejemplares similares