Quantification of In Vivo Metabolic Activity of CYP2D6 Genotypes and Alleles Through Population Pharmacokinetic Analysis of Vortioxetine

Assignment of CYP2D6 phenotype from genotype data can be challenging and despite efforts to standardize translation, there is currently no universally accepted method. To facilitate standardization, there remains a need to precisely quantify the in vivo function of different CYP2D6 genotypes. Vortio...

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Detalles Bibliográficos
Autores principales: Frederiksen, Trine, Areberg, Johan, Schmidt, Ellen, Bjerregaard Stage, Tore, Brøsen, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818194/
https://www.ncbi.nlm.nih.gov/pubmed/32599653
http://dx.doi.org/10.1002/cpt.1972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818194/
https://www.ncbi.nlm.nih.gov/pubmed/32599653
http://dx.doi.org/10.1002/cpt.1972

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