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Delayed treatment effects, treatment switching and heterogeneous patient populations: How to design and analyze RCTs in oncology

In the analysis of survival times, the logrank test and the Cox model have been established as key tools, which do not require specific distributional assumptions. Under the assumption of proportional hazards, they are efficient and their results can be interpreted unambiguously. However, delayed tr...

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Detalles Bibliográficos
Autores principales: Ristl, Robin, Ballarini, Nicolás M, Götte, Heiko, Schüler, Armin, Posch, Martin, König, Franz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818232/
https://www.ncbi.nlm.nih.gov/pubmed/32830428
http://dx.doi.org/10.1002/pst.2062