A Randomized, Single‐Blind, Placebo‐Controlled, 3‐Way Crossover Study to Evaluate the Effect of Therapeutic and Supratherapeutic Doses of Edaravone on QT/QTc Interval in Healthy Subjects

This randomized, single‐blind, 3‐way crossover study assessed the effect of edaravone on QT interval, including an exposure‐response analysis. Twenty‐seven healthy Japanese male volunteers, aged 20 to 49 years, were randomly assigned to receive a single intravenous dose of each treatment in 1 of 3 s...

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Detalles Bibliográficos
Autores principales: Shimizu, Hidetoshi, Inoue, Shinsuke, Endo, Mai, Nakamaru, Yoshinobu, Yoshida, Kaori, Natori, Tomoko, Kakubari, Masae, Akimoto, Makoto, Kondo, Kazuoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818234/
https://www.ncbi.nlm.nih.gov/pubmed/32543120
http://dx.doi.org/10.1002/cpdd.814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818234/
https://www.ncbi.nlm.nih.gov/pubmed/32543120
http://dx.doi.org/10.1002/cpdd.814

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