Effects of ABCB1, UGT1A1, and UGT1A9 Genetic Polymorphisms on the Pharmacokinetics of Sitafloxacin Granules in Healthy Subjects

Sitafloxacin, a new fluoroquinolone, has strong antibacterial activity. We evaluated the effects of sitafloxacin granules in single‐dose and multidose cohorts and the effects of ABCB1, UGT1A1, and UGT1A9 genetic polymorphisms on the pharmacokinetics (PK) of sitafloxacin in healthy subjects. The sing...

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Detalles Bibliográficos
Autores principales: Sun, Lu‐Ning, Sun, Guo‐Xian, Yang, Yu‐Qing, Shen, Ye, Huang, Feng‐Ru, Xie, Li‐Jun, Cheng, Juan, Zhang, Hong‐Wen, Zhang, Xue‐Hui, Liu, Yun, Wang, Yong‐Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818398/
https://www.ncbi.nlm.nih.gov/pubmed/32687695
http://dx.doi.org/10.1002/cpdd.848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818398/
https://www.ncbi.nlm.nih.gov/pubmed/32687695
http://dx.doi.org/10.1002/cpdd.848

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