CRISPR interference of nucleotide biosynthesis improves production of a single‐domain antibody in Escherichia coli

Growth decoupling can be used to optimize the production of biochemicals and proteins in cell factories. Inhibition of excess biomass formation allows for carbon to be utilized efficiently for product formation instead of growth, resulting in increased product yields and titers. Here, we used CRISPR...

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Detalles Bibliográficos
Autores principales: Landberg, Jenny, Wright, Naia Risager, Wulff, Tune, Herrgård, Markus J., Nielsen, Alex Toftgaard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818426/
https://www.ncbi.nlm.nih.gov/pubmed/32808670
http://dx.doi.org/10.1002/bit.27536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818426/
https://www.ncbi.nlm.nih.gov/pubmed/32808670
http://dx.doi.org/10.1002/bit.27536

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