Potential Dental Biofilm Inhibitors: Dynamic Combinatorial Chemistry Affords Sugar‐Based Molecules that Target Bacterial Glucosyltransferase

We applied dynamic combinatorial chemistry (DCC) to find novel ligands of the bacterial virulence factor glucosyltransferase (GTF) 180. GTFs are the major producers of extracellular polysaccharides, which are important factors in the initiation and development of cariogenic dental biofilms. Followin...

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Detalles Bibliográficos
Autores principales: Hartman, Alwin M., Jumde, Varsha R., Elgaher, Walid A. M., Te Poele, Evelien M., Dijkhuizen, Lubbert, Hirsch, Anna K. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818428/
https://www.ncbi.nlm.nih.gov/pubmed/32542998
http://dx.doi.org/10.1002/cmdc.202000222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818428/
https://www.ncbi.nlm.nih.gov/pubmed/32542998
http://dx.doi.org/10.1002/cmdc.202000222

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