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Reversion‐inducing cysteine‐rich protein with Kazal motifs and MT1‐MMP promote the formation of robust fibrillin fibers

Fibrillins (FBNs) form mesh‐like structures of microfibrils in various elastic tissues. RECK and FBN1 are co‐expressed in many human tissues, suggesting a functional relationship. We found that dermal FBN1 fibers show atypical morphology in mice with reduced RECK expression (RECK‐Hypo mice). Dermal...

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Detalles Bibliográficos
Autores principales: Matsuzaki, Tomoko, Keene, Douglas R., Nishimoto, Emi, Noda, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818472/
https://www.ncbi.nlm.nih.gov/pubmed/32730638
http://dx.doi.org/10.1002/jcp.29982