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Molecular characteristics and physiological roles of Na(+)–K(+)–Cl(−) cotransporter 2

Na(+)–K(+)–Cl(−) cotransporter 2 (NKCC2; SLC12A1) is an integral membrane protein that comes as three splice variants and mediates the cotranslocation of Na(+), K(+), and Cl(−) ions through the apical membrane of the thick ascending loop of Henle (TALH). In doing so, and through the involvement of o...

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Detalles Bibliográficos
Autores principales: Marcoux, Andree‐Anne, Tremblay, Laurence E., Slimani, Samira, Fiola, Marie‐Jeanne, Mac‐Way, Fabrice, Garneau, Alexandre P., Isenring, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818487/
https://www.ncbi.nlm.nih.gov/pubmed/32776569
http://dx.doi.org/10.1002/jcp.29997