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The use of host cell DNA methylation analysis in the detection and management of women with advanced cervical intraepithelial neoplasia: a review

This paper briefly reviews the role of hypermethylation of host cell genes in cervical carcinogenesis and discusses potential clinical applications of methylation analysis in the management of high‐risk HPV (hrHPV) ‐positive women. We argue that methylation assays can be used: 1. for primary triage...

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Detalles Bibliográficos
Autores principales: Kremer, WW, Steenbergen, RDM, Heideman, DAM, Kenter, GG, Meijer, CJLM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818489/
https://www.ncbi.nlm.nih.gov/pubmed/32619334
http://dx.doi.org/10.1111/1471-0528.16395