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Purification of Recombinant α-synuclein: A Comparison of Commonly Used Protocols

[Image: see text] The initial state of the intrinsically disordered protein α-synuclein (aSyn), e.g., the presence of oligomers and degradation products, or the presence of contaminants and adducts can greatly influence the aggregation kinetics and toxicity of the protein. Here, we compare four comm...

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Detalles Bibliográficos
Autores principales: Stephens, Amberley D., Matak-Vinkovic, Dijana, Fernandez-Villegas, Ana, Kaminski Schierle, Gabriele S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818547/
https://www.ncbi.nlm.nih.gov/pubmed/33237763
http://dx.doi.org/10.1021/acs.biochem.0c00725