Lactic acid promotes metastatic niche formation in bone metastasis of colorectal cancer

BACKGROUND: To investigate the effect of lactic acid (LA) on the progression of bone metastasis from colorectal cancer (CRC) and its regulatory effects on primary CD115 (+) osteoclast (OC) precursors. METHODS: The BrdU assay, Annexin-V/PI assay, TRAP staining and immunofluorescence were performed to...

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Detalles Bibliográficos
Autores principales: Qian, Jin, Gong, Zi-chen, Zhang, Yi-na, Wu, Hong-hua, Zhao, Jing, Wang, Li-ting, Ye, Li-juan, Liu, Da, Wang, Wei, Kang, Xia, Sheng, Jun, Xu, Wei, Liu, Xi-lin, Wu, Juan, Zheng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818572/
https://www.ncbi.nlm.nih.gov/pubmed/33478523
http://dx.doi.org/10.1186/s12964-020-00667-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818572/
https://www.ncbi.nlm.nih.gov/pubmed/33478523
http://dx.doi.org/10.1186/s12964-020-00667-x

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