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Lactic acid promotes metastatic niche formation in bone metastasis of colorectal cancer

BACKGROUND: To investigate the effect of lactic acid (LA) on the progression of bone metastasis from colorectal cancer (CRC) and its regulatory effects on primary CD115 (+) osteoclast (OC) precursors. METHODS: The BrdU assay, Annexin-V/PI assay, TRAP staining and immunofluorescence were performed to...

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Detalles Bibliográficos
Autores principales:	Qian, Jin, Gong, Zi-chen, Zhang, Yi-na, Wu, Hong-hua, Zhao, Jing, Wang, Li-ting, Ye, Li-juan, Liu, Da, Wang, Wei, Kang, Xia, Sheng, Jun, Xu, Wei, Liu, Xi-lin, Wu, Juan, Zheng, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818572/ https://www.ncbi.nlm.nih.gov/pubmed/33478523 http://dx.doi.org/10.1186/s12964-020-00667-x

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