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Strecker-Derived Methodology for Library Synthesis of N-Acylated α-Aminonitriles

[Image: see text] The Strecker reaction is a three-component condensation of an aldehyde, an amine, and hydrogen cyanide, delivering an α-amino carbonitrile. Despite extensive investigations, the possibility to use amides instead of amines as one of the three condensation partners has been largely n...

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Detalles Bibliográficos
Autores principales: Gonçalves, Pedro, Peeraer, Anke, Adriaenssens, Yves, Zonnekein, Lara, Franck, Philippe, Maes, Bert U. W., Augustyns, Koen, Van Der Veken, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818620/
https://www.ncbi.nlm.nih.gov/pubmed/33490792
http://dx.doi.org/10.1021/acsomega.0c04908