Synthesis, Anticancer Evaluation, Computer-Aided Docking Studies, and ADMET Prediction of 1,2,3-Triazolyl-Pyridine Hybrids as Human Aurora B Kinase Inhibitors

[Image: see text] A novel series of 1,2,3-triazolyl-pyridine hybrids were prepared through the reaction of the triazole derivative (1) with the appropriate aldehyde (2a–g) and malononitrile or ethyl cyanoacetate in the presence of ammonium acetate in refluxed acetic acid. The chemical composition of...

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Detalles Bibliográficos
Autores principales: Rashdan, Huda R.M., Shehadi, Ihsan A., Abdelmonsef, Abobakr H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818638/
https://www.ncbi.nlm.nih.gov/pubmed/33490804
http://dx.doi.org/10.1021/acsomega.0c05116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818638/
https://www.ncbi.nlm.nih.gov/pubmed/33490804
http://dx.doi.org/10.1021/acsomega.0c05116

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