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LncRNA NEAT1 promotes nucleus pulposus cell matrix degradation through regulating Nrf2/ARE axis

BACKGROUND: This study aimed to assess the role and mechanism of lncRNA NEAT1 in intervertebral disc degeneration (IVD). METHODS: LncRNA profile (GSE56081) between IVD and healthy control was downloaded from the Gene Expression Omnibus (GEO) database and analyzes differential lncRNA expression. Expr...

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Detalles Bibliográficos
Autores principales: Li, Cheng, Ma, Xinjian, Ni, Chenfei, Xu, Jingyan, Xie, Yinfei, Kan, Junwei, Wei, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818737/
https://www.ncbi.nlm.nih.gov/pubmed/33478594
http://dx.doi.org/10.1186/s40001-021-00481-2