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Peripherally misfolded proteins exacerbate ischemic stroke-induced neuroinflammation and brain injury

BACKGROUND: Protein aggregates can be found in peripheral organs, such as the heart, kidney, and pancreas, but little is known about the impact of peripherally misfolded proteins on neuroinflammation and brain functional recovery following ischemic stroke. METHODS: Here, we studied the ischemia/repe...

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Detalles Bibliográficos
Autores principales: Liu, Yanying, Subedi, Kalpana, Baride, Aravind, Romanova, Svetlana, Callegari, Eduardo, Huber, Christa C., Wang, Xuejun, Wang, Hongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818745/
https://www.ncbi.nlm.nih.gov/pubmed/33472658
http://dx.doi.org/10.1186/s12974-021-02081-7