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Mechanisms underlying low-clinical responses to PD-1/PD-L1 blocking antibodies in immunotherapy of cancer: a key role of exosomal PD-L1

Exosomes, as the main group of extracellular vesicles, are biologically active lipid-bilayer vesicles that are naturally released from different types of normal or tumor cells. These vesicles play an important role in intercellular communication and influence the extracellular environment and the im...

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Detalles Bibliográficos
Autores principales: Yin, Zi, Yu, Min, Ma, Tingting, Zhang, Chuanzhao, Huang, Shanzhou, Karimzadeh, Mohammad Reza, Momtazi-Borojeni, Amir Abaas, Chen, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818841/
https://www.ncbi.nlm.nih.gov/pubmed/33472857
http://dx.doi.org/10.1136/jitc-2020-001698