Metastasis-associated macrophages constrain antitumor capability of natural killer cells in the metastatic site at least partially by membrane bound transforming growth factor β

BACKGROUND: Metastatic breast cancer is a leading cause of cancer-related death in women worldwide. Infusion of natural killer (NK) cells is an emerging immunotherapy for such malignant tumors, although elimination of the immunosuppressive tumor environment is required to improve its efficacy. The e...

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Detalles Bibliográficos
Autores principales: Brownlie, Demi, Doughty-Shenton, Dahlia, YH Soong, Daniel, Nixon, Colin, O Carragher, Neil, M Carlin, Leo, Kitamura, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818844/
https://www.ncbi.nlm.nih.gov/pubmed/33472858
http://dx.doi.org/10.1136/jitc-2020-001740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818844/
https://www.ncbi.nlm.nih.gov/pubmed/33472858
http://dx.doi.org/10.1136/jitc-2020-001740

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