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Neuronal protein-tyrosine phosphatase 1B hinders sensory-motor functional recovery and causes affective disorders in two different focal ischemic stroke models

Ischemic brain injury causes neuronal death and inflammation. Inflammation activates protein-tyrosine phosphatase 1B (PTP1B). Here, we tested the significance of PTP1B activation in glutamatergic projection neurons on functional recovery in two models of stroke: by photothrombosis, focal ischemic le...

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Detalles Bibliográficos
Autores principales: Cruz, Shelly A., Qin, Zhaohong, Ricke, Konrad M., Stewart, Alexandre F.R., Chen, Hsiao-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818877/
https://www.ncbi.nlm.nih.gov/pubmed/32788467
http://dx.doi.org/10.4103/1673-5374.286970