Leber’s Hereditary Optic Neuropathy: the roles of mitochondrial transfer RNA variants

Leber’s Hereditary Optic Neuropathy (LHON) was a common maternally inherited disease causing severe and permanent visual loss which mostly affects males. Three primary mitochondrial DNA (mtDNA) mutations, ND1 3460G>A, ND4 11778G>A and ND6 14484T>C, which affect genes encoding respiratory ch...

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Detalles Bibliográficos
Autores principales: Ding, Yu, Zhuo, Guangchao, Guo, Qinxian, Li, Meiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819119/
https://www.ncbi.nlm.nih.gov/pubmed/33552719
http://dx.doi.org/10.7717/peerj.10651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819119/
https://www.ncbi.nlm.nih.gov/pubmed/33552719
http://dx.doi.org/10.7717/peerj.10651

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