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miR-636 inhibits EMT, cell proliferation and cell cycle of ovarian cancer by directly targeting transcription factor Gli2 involved in Hedgehog pathway

BACKGROUND: Hedgehog (Hh) signaling pathway, which is essential for cell proliferation and differentiation, is noted to be aberrantly activated in tumor from increasing studies in recent years. MicroRNAs (miRNAs) as an important non-coding RNA in cells have been proven to possess a regulatory role s...

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Detalles Bibliográficos
Autores principales: Ma, Jiong, Zhou, Chunxia, Chen, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819188/
https://www.ncbi.nlm.nih.gov/pubmed/33472614
http://dx.doi.org/10.1186/s12935-020-01725-7