PDGFRβ is an essential therapeutic target for BRCA1-deficient mammary tumors

BACKGROUND: Basal-like breast cancers (BLBCs) are a leading cause of cancer death due to their capacity to metastasize and lack of effective therapies. More than half of BLBCs have a dysfunctional BRCA1. Although most BRCA1-deficient cancers respond to DNA-damaging agents, resistance and tumor recur...

Descripción completa

Detalles Bibliográficos
Autores principales: Bai, Feng, Liu, Shiqin, Liu, Xiong, Hollern, Daniel P., Scott, Alexandria, Wang, Chuying, Zhang, Lihan, Fan, Cheng, Fu, Li, Perou, Charles M., Zhu, Wei-Guo, Pei, Xin-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819225/
https://www.ncbi.nlm.nih.gov/pubmed/33478572
http://dx.doi.org/10.1186/s13058-021-01387-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819225/
https://www.ncbi.nlm.nih.gov/pubmed/33478572
http://dx.doi.org/10.1186/s13058-021-01387-x

Ejemplares similares