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Effect of host-mimicking medium and biofilm growth on the ability of colistin to kill Pseudomonas aeruginosa

In vivo biofilms cause recalcitrant infections with extensive and unpredictable antibiotic tolerance. Here, we demonstrate increased tolerance of colistin by Pseudomonas aeruginosa when grown in medium that mimics cystic fibrosis (CF) sputum versus standard medium in in vitro biofilm assays, and dra...

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Detalles Bibliográficos
Autores principales: Sweeney, Esther, Sabnis, Akshay, Edwards, Andrew M., Harrison, Freya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819359/
https://www.ncbi.nlm.nih.gov/pubmed/33253080
http://dx.doi.org/10.1099/mic.0.000995